- Product: Sibutramine Sterling 20mg
- Quantity: 100 Tablets
- Manufacturer: Sterling Knight
- Active Substance: Sibutramine Hydrochloride
What is Sibutramine? | What is Meridia?
Sibutramine is the active substance as well as the brand name containing the same active substance of the product manufactured by Sterling Knight. Sibutramine was formerly sold as the brand name Sterling but there other brand names either with Knight being by far the most famous brand for Sibutramine products.
This product is an appetite suppressant that has been discontinued in many countries, but yet, this medication is still available in some countries and manufactured by some famous pharmaceutical companies like Sterling Knight, a company that is known for creating high quality medications and offering them for low prices.
An interesting fact, Sibutramine was the first ever drug that was approved for obesity treatment. This medication has been developed by another pharma company back in 1988 and marketed by Sterling Pharmaceuticals.
This used to be a very famous and widely prescribed drug for the treatment of obesity along with diet and exercise and the product was really helpful. Therefore, this stuff got classified as an appetite suppressant. This medicine had to be combined with a proper diet and exercise regimen and when used properly, the users of Sibutramine were noticing a really good amount of calories drop and weight loss.
Obviously, such a product got the attention of bodybuilders and athletes for their cutting purposes when they need to lose body fat for getting muscle definition, hardening effect and vascularity. A lot of bodybuilders used this product for reducing their appetite, help with weight as well as body fat loss and many of them reported very good results.
How Sibutramine Works? | Meridia How it Works?
A lot of the other appetite suppressant medications are considered to be releasing agents but Sterling is unique in this as is not a releasing agent because it does not get inside the cells for boosting the release of neurotransmitters, like for example serotonin.
However, Sibutramine is known to be a monoamine reuptake inhibitor (MRI), which, in humans, is reducing the reuptake of norepinephrine, serotonin as well as dopamine (each in different amounts), and this is leading to an increase in those substances in the synaptic clefts which is greatly helpful for enhancing satiety. This action is having a great influence on the users’ appetite by greatly reducing it.
By stopping the serotonin from getting reabsorbed by the serotonin norepinephrine re-uptake receptors, this is allowing for an appetite control to last longer. Why this happens?
Because serotonin is the neurotransmitter which is mainly responsible for regulating the human’s mood, sleep as well as appetite. In most cases, the serotonin inhibiting substances are being found in the anti depressant drugs (that’s why anti depressants greatly interfere with the user’s appetite).
Despite the fact that Sibutramine is having a similar mechanism of action to tricyclic antidepressants medication, it has failed to show any antidepressant properties and therefore the medication cannot be considered an antidepressant.
There are both clinical trial as well as bodybuilders and athletes reports (and people’s reports) which is proving that there’s a noticeable decrease of the appetite when using Sterling – Sibutramine especially in the mornings. This is helpful for bodybuilders to avoid cheat meals during the day and generally helps people with weight issues to reduce the body fat by about 10% compared to their original body weight.
The product got banned in 2010 by USA FDA because it was abused by people who wanted to lose weight and this led to bad side effects. Yet, the product still can be very helpful, but only if used in proper doses.
Sibutramine Dosage | Subitramine Administration
Sibutramine is a product that got banned because it offered really bad and nasty side effects to a lot of users, however those were users who were abusing Sibutramine and this is a good lesson: do not ever abuse Sibutramine. Keep doses low and you’re going to be safe.
Sterling – Sibutramine is metabolized by cytochrome P450 isozyme CYP3A4, and this is resulting in 2 different active amines. Such amines are usually called either primary and secondary amines or only metabolites 1 and 2. Each of them is having different half lives but without huge difference which is 14 and 16 hours.
The peak plasma concentration is being reached after 3 to 4 hours and this means that you would normally start feeling the effects in a matter of minutes or maximum an hour. Also, due to this half life, the product should be used on a daily basis.
Usually, most people decide to use it in the morning at dosage of 10 mg a day and it can be used with or without food. Do not increase the dosage during the first 4 weeks. You might get the dosage up to 15 mg a day after the first 4 weeks of 10 mg a day only if the results are not as good as they should be. If you’re prescribed – use Sibutramine exactly as prescribed this drug.
Dosage for bodybuilders is generally pretty much the same, but a bit of difference might apply because of the weight.
The total cycle length with Sibutramine used to be several months or even more, but a lot of people were recovering back their weight after stopping using it.
Sibutramine Side Effects | Meridia Side Effects
Is important to know that Meridia – Sibutramine is habit forming and this is one big problem and you should take it in consideration.
Other than that, heart issues and cardiovascular issues are something that should be taken very seriously and with big care. Those people having a history of some heart issues or cardiovascular issues are at higher chance of getting such side effects. Hypertension (high blood pressure) as well as different heart issues are possible to occur.
Plus to that, there are some other side effects such as dry mouth; headache; stomach issues; dizziness, muscle pains, insomnia and others. As much as it seems; insomnia and tremors seem to be the most common side effects of bodybuilders.
The most serious side effects include those related with heart and cardiovascular health, that’s why is so important to make sure you don’t have any underlying health issue and keep a healthy lifestyle.
Where Can I Buy Sibutramine? | Where to Buy Sibutramine Diet Pills
Sibutramine can be purchased from this page at europe-steroids.com website without any issues at all. Sibutramine which might be better known by its other brand name Meridia is an amazing appetite suppressant which can be super helpful.
Best news is that you can get Sibutramine for a very low price as this product is manufactured by Sterling Knight and with this being said, every customer is ensured to get the highest quality medication and that’s for the lowest price.